The Originals — D-Nice, Stretch Armstrong, Clark Kent, Tony Touch and Rich Medina — took over D-Nice’s Club Quarantine and spun an hour each on Saturday for a crowd including Diplo, Nile Rodgers, Donnie Wahlberg, Diddy, Jody Watley, Melba Moore and Fat Joe.

On Sunday, celeb doula Latham Thomas celebrated her 40th birthday with client Ashley Graham and pal Estelle at the virtual hot spot.

From her Upper East Side pad, DJ Marjorie “Mad Marj” Gubelmann launched a Saturday “tea dance” for pals such as Peter Davis, Rachel Roy and Kevin Liles.

DJ couple Kiss and M.O.S. battled at M.O.S.’s Club Insomnia party, where he played a 13-hour set.

Swizz Beatz hosted late-night “Zone Radio” pop- up, and his wife, Alicia Keys, made a cameo.