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        <title><![CDATA[Johnson & Johnson starts human vaccine trials after monkey study]]></title>
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            <media:title type="html">Johnson & Johnson starts human vaccine trials after monkey study</media:title>
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        <content:encoded><![CDATA[<p>Johnson &amp; Johnson kicked off human trials of <strong>its experimental COVID-19 vaccine</strong> Thursday, after the shots already proved successful in protecting monkeys, the drugmaker announced.</p><p>Company honchos pointed to a new study which found that five out of six primates who got the single-dose shot were protected from infection when exposed to the coronavirus, as measured by its presence in nasal swabs.</p><p>“This gives us confidence that we can test a single-shot vaccine in this epidemic and learn whether it has a protective effect in humans,” Dr. Paul Stoffels, J&amp;J’s chief scientific officer <strong>told Reuters</strong>.</p><p>The study, published <strong>Thursday in the journal Nature</strong>, also found that six out of six of the monkeys were protected from lung disease related to COVID-19.</p><p>J&amp;J said it will now test its vaccine candidate on more than 1,000 healthy adults aged 18 to 55, along with people over the age of 65 in early-stage human trials in the United States and Belgium.</p><p>In other cases, researchers found a second shot significantly increases protection from disease — but a single-shot vaccine is crucial during a pandemic because it reduces issues such as getting people to come back for a second dose, Stoffels said.</p><p>The company plans to tackle the question of whether the vaccine should be a one- or two-dose shot during phase one of the human trial, he said.</p><p>The clinical trial is one of more than 30 human trials for coronavirus vaccines that are underway worldwide, according to the <strong>New York Times</strong>, which noted some experts were optimistic about the results of the new study.</p><p>“This week has been good — now we have two vaccines that work in monkeys,” said Angela Rasmussen, a virologist at Columbia University who was not involved in the research. “It’s nice to be upbeat for a change.”</p><p>The US government is pouring $456 million into J&amp;J’s vaccine development <strong>as part of an effort to speed along production of a vaccine for COVID-19</strong>, which has killed more than 667,000 people worldwide, including more than 150,000 Americans, according to Johns Hopkins University data.</p>]]></content:encoded>
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