“Caterina and Rob have separated,” their reps confirmed to People on Friday in a joint statement. “They remain friends and are committed to co-parenting their children in a spirit of love.”

Scorsone, who plays Amelia Shepherd on the long-running medical drama, and Giles wed in 2009. Formerly a musician who played with The Police’s Andy Summers, Giles pivoted to film and television writing. According to IMDb, he’s written two episodes of the “Grey’s Anatomy” spin-off series, “Station 19.”

The couple share three daughters: Eliza, 7, Paloma “Pippa” Michaela, 3, and Arwen Lucinda, born in December 2019.

Scorsone, 38, has been open about her struggles in dealing with Pippa’s Down syndrome diagnosis, telling the “Motherly” podcast in 2019 that it sent her into a “tailspin” at first.